CAS 1346704-33-3|GSK 343

Rhagymadrodd
GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM, 60-fold selective for EZH1 and >1000-plygiad dethol ar gyfer histone methyltransferases eraill.

Manyleb CAS 1346704-33-3|GSK 343

Synthesis oCAS 1346704-33-3|GSK 343

Amodau

Gyda dichloro(1,1'-bis(deuffenylphosphanyl)ferrosen)palladium(II)*CH2Cl2; sodiwm hydrogencarbonad Mewn 1,4-deuocsan; dŵr ar 110 gradd; am 0.333333h; Awyrgylch anadweithiol; Tiwb wedi'i selio; Arbelydru microdon;

Cyfeiriad

Verma, Sharad K.; Tian, ​​Xinrong; Lafrance, Louis V.; Duquenne, Céline; Suarez, Dominic P.; Newlander, Kenneth A.; Romeril, Stuart P.; (…) Creasy, Caretha L.; Miller, William H.

[Llythyrau Cemeg Feddyginiaethol ACS, 2012, cyf. 3, # 12, t. 1091 - 1096]

Tagiau poblogaidd: cas 1346704-33-3|gsk 343, pris, dyfynbris, gostyngiad, mewn stoc, ar werth